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Minisymposium

Me 3 Computational biomechanics, towards the overall human
Markus Böl (TU Braunschweig), Oliver Röhrle (U Stuttgart)

Computational biomechanics requires an interdisciplinary environment open for innovative ideas and cross-disciplinary collaborations between many different scientists researching in the broad field of simulation technologies, material sciences, engineering, computational physiology, medicine, biology, and many other fields. Just like for classical engineering type applications, e.g. the automotive industry or in aerospace engineering, there is a great need for new simulation technologies to augment or substitute classical experiments and to make simulation-based predictions. The goal has to be to build up numerical computer models and simulation tools combining multiple physics and scales to generate virtual testing environments, e.g. for prototyping new implants or predicting its functionality for a subject-specific case. From a computational point of view, the development of new and integrated multi-scale algorithms exploiting emerging technologies, algorithms, and high-performance computing architectures are essential to tackle the complex and challenging real-world applications. The successful transition from basic research in computational biomechanics to customised solutions for medical challenges will push the boundaries of modern medicine through personalised, predictable, and individualised health care, and will thereby provide an overall positive impact to our socio-economic system.

Nic Smith: Translating computational cardiac biomechanics into the clinic
Wolfgang A. Wall: Towards mixed effect modeling of patient specific aneurysmatic arterial wall behavior and strength
Wolfgang Ehlers: Modelling and Remodelling of Biological Tissue in the Framework of Continuum Biomechanics
Gerhard Holzapfel: Multi-scale modeling of endothelial cells
Paul Watton: Patient-specific models of cerebral aneurysm evolution